p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations
نویسندگان
چکیده
منابع مشابه
p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations
STUDY QUESTION Is the environmental endocrine disruptor p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) able to induce non-genomic changes in human sperm and consequently affect functional sperm parameters? SUMMARY ANSWER p,p'-DDE promoted Ca(2+) flux into human sperm by activating CatSper channels even at doses found in human reproductive fluids, ultimately compromising sperm parameters imp...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2013
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/det372